GO Annotations Graph

• Symbol: Dusp19
• Name: dual specificity phosphatase 19
• ID: MGI:1915332

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008579	JUN kinase phosphatase activity	IBA	J:265628
Molecular Function	GO:0008579	JUN kinase phosphatase activity	IDA	J:77441
Molecular Function	GO:0005078	MAP-kinase scaffold activity	IDA	J:77617
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	IPI	J:77617
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	IPI	J:77617
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:77441
Molecular Function	GO:0005515	protein binding	IPI	J:77617
Molecular Function	GO:0030295	protein kinase activator activity	IDA	J:77617
Molecular Function	GO:0004860	protein kinase inhibitor activity	IDA	J:77617
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IEA	J:72245
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IEA	J:72245
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	ISO	J:164563
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IDA	J:73204
Molecular Function	GO:0008330	protein tyrosine/threonine phosphatase activity	IDA	J:77441
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:77441
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0007254	JNK cascade	IDA	J:77617
Biological Process	GO:0046329	negative regulation of JNK cascade	IDA	J:77617
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IDA	J:77617
Biological Process	GO:0043409	negative regulation of MAPK cascade	IDA	J:77441
Biological Process	GO:0006469	negative regulation of protein kinase activity	IDA	J:77617
Biological Process	GO:0046330	positive regulation of JNK cascade	IDA	J:77617
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IDA	J:77617
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:77617
Biological Process	GO:0045860	positive regulation of protein kinase activity	IDA	J:77617
Biological Process	GO:0006470	protein dephosphorylation	IDA	J:77441
Biological Process	GO:0043405	regulation of MAP kinase activity	IBA	J:265628