GO Annotations Graph

• Symbol: Ndnf
• Name: neuron-derived neurotrophic factor
• ID: MGI:1915419

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005539	glycosaminoglycan binding	IDA	J:139122
Molecular Function	GO:0008201	heparin binding	IBA	J:265628
Molecular Function	GO:0008201	heparin binding	IDA	J:139122
Cellular Component	GO:0031012	extracellular matrix	IDA	J:139122
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:139122
Biological Process	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	IMP	J:291089
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0001764	neuron migration	ISO	J:164563
Biological Process	GO:0007263	nitric oxide mediated signal transduction	ISO	J:164563
Biological Process	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	IBA	J:265628
Biological Process	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	IDA	J:139122
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	IDA	J:139122
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0002931	response to ischemia	IDA	J:215950
Biological Process	GO:0061042	vascular wound healing	IMP	J:215950