GO Annotations Graph

• Symbol: Mcoln2
• Name: mucolipin 2
• ID: MGI:1915529

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:239875
Molecular Function	GO:0005261	monoatomic cation channel activity	IEA	J:72247
Molecular Function	GO:0072345	NAADP-sensitive calcium-release channel activity	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0055037	recycling endosome	IDA	J:239875
Cellular Component	GO:0055037	recycling endosome	IDA	J:239875
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:1905517	macrophage migration	IMP	J:239875
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1990266	neutrophil migration	IMP	J:239875
Biological Process	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production	IMP	J:239875
Biological Process	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	IMP	J:239875
Biological Process	GO:0032722	positive regulation of chemokine production	IMP	J:239875
Biological Process	GO:0071642	positive regulation of macrophage inflammatory protein 1 alpha production	IMP	J:239875
Biological Process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	IMP	J:239875
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	IMP	J:239875