GO Annotations Graph

• Symbol: Tmem109
• Name: transmembrane protein 109
• ID: MGI:1915789

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:195510
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:73065
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031965	nuclear membrane	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0016529	sarcoplasmic reticulum	IEA	J:60000
Biological Process	GO:0071480	cellular response to gamma radiation	IBA	J:265628
Biological Process	GO:0071480	cellular response to gamma radiation	ISO	J:195510
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IBA	J:265628
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:157864
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060548	negative regulation of cell death	IBA	J:265628
Biological Process	GO:0043069	negative regulation of programmed cell death	ISO	J:195510
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000