GO Annotations Graph

• Symbol: Lamtor5
• Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
• ID: MGI:1915826

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	NAS	J:320089
Cellular Component	GO:0005765	lysosomal membrane	NAS	J:320116
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0071986	Ragulator complex	ISO	J:164563
Cellular Component	GO:0071986	Ragulator complex	IBA	J:265628
Biological Process	GO:0071230	cellular response to amino acid stimulus	ISO	J:164563
Biological Process	GO:0071230	cellular response to amino acid stimulus	IBA	J:265628
Biological Process	GO:0043066	negative regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	ISO	J:164563
Biological Process	GO:0032008	positive regulation of TOR signaling	ISO	J:164563
Biological Process	GO:1904263	positive regulation of TORC1 signaling	IBA	J:265628
Biological Process	GO:0061462	protein localization to lysosome	ISO	J:164563
Biological Process	GO:0008361	regulation of cell size	ISO	J:164563
Biological Process	GO:0038202	TORC1 signaling	NAS	J:320116