GO Annotations Graph

• Symbol: Tmed10
• Name: transmembrane p24 trafficking protein 10
• ID: MGI:1915831

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008320	protein transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0019905	syntaxin binding	ISO	J:164563
Cellular Component	GO:0005801	cis-Golgi network	ISS	J:121526
Cellular Component	GO:0005801	cis-Golgi network	ISO	J:155856
Cellular Component	GO:0030137	COPI-coated vesicle	ISO	J:155856
Cellular Component	GO:0030137	COPI-coated vesicle	IBA	J:265628
Cellular Component	GO:0030134	COPII-coated ER to Golgi transport vesicle	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:164563
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:155856
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IBA	J:265628
Cellular Component	GO:0070765	gamma-secretase complex	ISO	J:164563
Cellular Component	GO:0070765	gamma-secretase complex	ISO	J:155856
Cellular Component	GO:0070765	gamma-secretase complex	IDA	J:108398
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0000139	Golgi membrane	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0030667	secretory granule membrane	IDA	J:121526
Cellular Component	GO:0042589	zymogen granule membrane	ISO	J:155856
Cellular Component	GO:0042589	zymogen granule membrane	IDA	J:121526
Biological Process	GO:0035964	COPI-coated vesicle budding	ISO	J:164563
Biological Process	GO:0106273	cytosol to ERGIC protein transport	ISO	J:164563
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA	J:265628
Biological Process	GO:0007030	Golgi organization	ISO	J:155856
Biological Process	GO:0007030	Golgi organization	IDA	J:95650
Biological Process	GO:0007030	Golgi organization	IBA	J:265628
Biological Process	GO:0006886	intracellular protein transport	ISO	J:164563
Biological Process	GO:0006886	intracellular protein transport	TAS	J:121526
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:1902960	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	IMP	J:108398
Biological Process	GO:0032732	positive regulation of interleukin-1 production	IMP	J:292437
Biological Process	GO:0032732	positive regulation of interleukin-1 production	ISO	J:164563
Biological Process	GO:0050714	positive regulation of protein secretion	ISO	J:164563
Biological Process	GO:0050714	positive regulation of protein secretion	IMP	J:292437
Biological Process	GO:0106272	protein localization to ERGIC	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0045055	regulated exocytosis	IEP	J:121526
Biological Process	GO:1902003	regulation of amyloid-beta formation	ISO	J:164563
Biological Process	GO:0048199	vesicle targeting, to, from or within Golgi	IEP	J:121526
Biological Process	GO:0016192	vesicle-mediated transport	IEA	J:60000