GO Annotations Graph

• Symbol: Cthrc1
• Name: collagen triple helix repeat containing 1
• ID: MGI:1915838

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005109	frizzled binding	IPI	J:140886
Molecular Function	GO:0005109	frizzled binding	IPI	J:140886
Molecular Function	GO:0005109	frizzled binding	IPI	J:140886
Molecular Function	GO:0005515	protein binding	IPI	J:140886
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:140886
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:140886
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:140886
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0031012	extracellular matrix	ISO	J:73065
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	ISO	J:73065
Cellular Component	GO:0016528	sarcoplasm	IDA	J:159810
Biological Process	GO:0016477	cell migration	ISO	J:155856
Biological Process	GO:0016477	cell migration	ISO	J:73065
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:140886
Biological Process	GO:0090177	establishment of planar polarity involved in neural tube closure	IGI	J:140886
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IGI	J:140886
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IDA	J:140886
Biological Process	GO:0043932	ossification involved in bone remodeling	IMP	J:143940
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:143940
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:143940
Biological Process	GO:0033687	osteoblast proliferation	IMP	J:143940
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IMP	J:143940
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	IMP	J:143940
Biological Process	GO:0032092	positive regulation of protein binding	IDA	J:140886
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IMP	J:140886