GO Annotations Graph

• Symbol: Mtcl1
• Name: microtubule crosslinking factor 1
• ID: MGI:1915867

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IDA	J:206886
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:206886
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:206886
Cellular Component	GO:0016327	apicolateral plasma membrane	IDA	J:206886
Cellular Component	GO:0016327	apicolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IDA	J:206886
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IEA	J:72247
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:206886
Cellular Component	GO:0016328	lateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0097427	microtubule bundle	IDA	J:206886
Cellular Component	GO:0097427	microtubule bundle	IBA	J:265628
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0030496	midbody	IDA	J:206886
Cellular Component	GO:0030496	midbody	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0000922	spindle pole	IDA	J:206886
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	IBA	J:265628
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IDA	J:206886
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IBA	J:265628
Biological Process	GO:0001578	microtubule bundle formation	IDA	J:206886
Biological Process	GO:0001578	microtubule bundle formation	IBA	J:265628
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	IDA	J:206886
Biological Process	GO:0010506	regulation of autophagy	IEA	J:72247