GO Annotations Graph

• Symbol: Tab2
• Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
• ID: MGI:1915902

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	ISO	J:164563
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:120934
Molecular Function	GO:0005515	protein binding	IPI	J:206842
Molecular Function	GO:0005515	protein binding	IPI	J:201312
Molecular Function	GO:0043130	ubiquitin binding	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-209329
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-1253318
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-1253330
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-1253330
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	IBA	J:265628
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:164563