GO Annotations Graph

• Symbol: Prickle1
• Name: prickle planar cell polarity protein 1
• ID: MGI:1916034

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:321396
Molecular Function	GO:0005515	protein binding	IPI	J:249862
Molecular Function	GO:0005515	protein binding	IPI	J:249862
Molecular Function	GO:0005515	protein binding	IPI	J:249862
Molecular Function	GO:0005515	protein binding	IPI	J:155488
Molecular Function	GO:0044877	protein-containing complex binding	IDA	J:249862
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0031254	cell trailing edge	IDA	J:249862
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IMP	J:249862
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:183948
Cellular Component	GO:0005634	nucleus	IDA	J:183948
Cellular Component	GO:0005634	nucleus	IDA	J:183948
Cellular Component	GO:0005634	nucleus	IDA	J:183948
Cellular Component	GO:0000502	proteasome complex	IDA	J:213772
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:301041
Biological Process	GO:1905070	anterior visceral endoderm cell migration	IMP	J:151993
Biological Process	GO:0035904	aorta development	IMP	J:222159
Biological Process	GO:0006915	apoptotic process	IMP	J:202865
Biological Process	GO:0007409	axonogenesis	IMP	J:213772
Biological Process	GO:0071711	basement membrane organization	IMP	J:301041
Biological Process	GO:0030282	bone mineralization	IMP	J:202865
Biological Process	GO:0055013	cardiac muscle cell development	IMP	J:213772
Biological Process	GO:0055013	cardiac muscle cell development	IMP	J:229529
Biological Process	GO:0016477	cell migration	IMP	J:229529
Biological Process	GO:0016477	cell migration	IGI	J:249862
Biological Process	GO:0016477	cell migration	IGI	J:249862
Biological Process	GO:0016477	cell migration	IMP	J:249862
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:301041
Biological Process	GO:0016043	cellular component organization	IMP	J:213772
Biological Process	GO:0060271	cilium assembly	IMP	J:229529
Biological Process	GO:0044782	cilium organization	IMP	J:229529
Biological Process	GO:0061303	cornea development in camera-type eye	IMP	J:258233
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0007010	cytoskeleton organization	IMP	J:229529
Biological Process	GO:0030705	cytoskeleton-dependent intracellular transport	IMP	J:301041
Biological Process	GO:0016358	dendrite development	IMP	J:198157
Biological Process	GO:1990403	embryonic brain development	IMP	J:126805
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:202865
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:202865
Biological Process	GO:0035880	embryonic nail plate morphogenesis	IMP	J:202865
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	IMP	J:249862
Biological Process	GO:0061159	establishment of bipolar cell polarity involved in cell morphogenesis	IMP	J:151993
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:213772
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:229529
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:249862
Biological Process	GO:0030010	establishment of cell polarity	IGI	J:249862
Biological Process	GO:0030010	establishment of cell polarity	IGI	J:249862
Biological Process	GO:0045184	establishment of protein localization	IMP	J:249862
Biological Process	GO:0007163	establishment or maintenance of cell polarity	IMP	J:202865
Biological Process	GO:0085029	extracellular matrix assembly	IMP	J:151993
Biological Process	GO:0061029	eyelid development in camera-type eye	IMP	J:258233
Biological Process	GO:0060325	face morphogenesis	IMP	J:202865
Biological Process	GO:0060325	face morphogenesis	IMP	J:213772
Biological Process	GO:0120181	focal adhesion disassembly	IMP	J:249862
Biological Process	GO:0010467	gene expression	IMP	J:202865
Biological Process	GO:0010467	gene expression	IMP	J:213772
Biological Process	GO:0010467	gene expression	IMP	J:229529
Biological Process	GO:0010467	gene expression	IMP	J:258233
Biological Process	GO:0007507	heart development	IMP	J:229529
Biological Process	GO:0060173	limb development	IMP	J:202865
Biological Process	GO:0035108	limb morphogenesis	IMP	J:213772
Biological Process	GO:0060485	mesenchyme development	IMP	J:258233
Biological Process	GO:0090307	mitotic spindle assembly	IMP	J:151993
Biological Process	GO:0035264	multicellular organism growth	IMP	J:202865
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0001843	neural tube closure	ISO	J:164563
Biological Process	GO:0001843	neural tube closure	IMP	J:213772
Biological Process	GO:0031175	neuron projection development	IMP	J:126805
Biological Process	GO:1990138	neuron projection extension	IMP	J:247070
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:198157
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:213772
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:229529
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IMP	J:301041
Biological Process	GO:0061865	polarized secretion of basement membrane proteins in epithelium	IMP	J:301041
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:202865
Biological Process	GO:0090009	primitive streak formation	IMP	J:151993
Biological Process	GO:0012501	programmed cell death	IMP	J:258233
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	ISO	J:155856
Biological Process	GO:0061326	renal tubule development	IMP	J:213772
Biological Process	GO:0051602	response to electrical stimulus	IMP	J:169136
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:169136
Biological Process	GO:0070075	tear secretion	IMP	J:301041
Biological Process	GO:0009888	tissue development	IMP	J:213772
Biological Process	GO:0001894	tissue homeostasis	IMP	J:258233
Biological Process	GO:0016192	vesicle-mediated transport	IMP	J:301041
Biological Process	GO:0016055	Wnt signaling pathway	IMP	J:213772
Biological Process	GO:0016055	Wnt signaling pathway	IMP	J:229529
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IMP	J:258233