GO Annotations Graph

• Symbol: Prrt2
• Name: proline-rich transmembrane protein 2
• ID: MGI:1916267

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:255335
Molecular Function	GO:0005515	protein binding	IPI	J:235086
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:231224
Molecular Function	GO:0017075	syntaxin-1 binding	IDA	J:255335
Cellular Component	GO:0043679	axon terminus	IDA	J:255335
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:235086
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:235086
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:235086
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:235086
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:235086
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:235086
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:235086
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:188761
Cellular Component	GO:0043005	neuron projection	ISO	J:231224
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:231224
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0098793	presynapse	IDA	J:235086
Cellular Component	GO:0098793	presynapse	IDA	J:255335
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IMP	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IEP	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IEP	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IMP	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:235086
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:255335
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:255335
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:255335
Cellular Component	GO:0042734	presynaptic membrane	IEP	J:255335
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:255335
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:255335
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:235086
Cellular Component	GO:0031982	vesicle	IDA	J:255335
Biological Process	GO:1905513	negative regulation of short-term synaptic potentiation	IMP	J:255335
Biological Process	GO:0035544	negative regulation of SNARE complex assembly	IMP	J:255335
Biological Process	GO:0050884	neuromuscular process controlling posture	ISO	J:73065
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IMP	J:235086
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:235086
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:235086
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IPI	J:235086
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:235086
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IMP	J:235086
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IPI	J:235086
Biological Process	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	IMP	J:235086