GO Annotations Graph

• Symbol: Chac1
• Name: ChaC, cation transport regulator 1
• ID: MGI:1916315

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003839	gamma-glutamylcyclotransferase activity	IBA	J:265628
Molecular Function	GO:0061928	glutathione specific gamma-glutamylcyclotransferase activity	IEA	J:72245
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0005112	Notch binding	IDA	J:184017
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9653904
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:184017
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006751	glutathione catabolic process	IBA	J:265628
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0010955	negative regulation of protein processing	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0022008	neurogenesis	IMP	J:184017
Biological Process	GO:0007219	Notch signaling pathway	IEA	J:60000
Biological Process	GO:0006986	response to unfolded protein	IEA	J:60000