GO Annotations Graph

• Symbol: Ddah1
• Name: dimethylarginine dimethylaminohydrolase 1
• ID: MGI:1916469

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016597	amino acid binding	ISO	J:155856
Molecular Function	GO:0016597	amino acid binding	IBA	J:265628
Molecular Function	GO:0016403	dimethylargininase activity	ISO	J:164563
Molecular Function	GO:0016403	dimethylargininase activity	ISO	J:155856
Molecular Function	GO:0016403	dimethylargininase activity	IMP	J:182373
Molecular Function	GO:0016403	dimethylargininase activity	IBA	J:265628
Molecular Function	GO:0016403	dimethylargininase activity	ISO	J:81494
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:81494
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Biological Process	GO:0006527	arginine catabolic process	ISO	J:164563
Biological Process	GO:0006525	arginine metabolic process	ISO	J:155856
Biological Process	GO:0006525	arginine metabolic process	IBA	J:265628
Biological Process	GO:0000052	citrulline metabolic process	ISO	J:164563
Biological Process	GO:0000052	citrulline metabolic process	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:1900038	negative regulation of cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0043116	negative regulation of vascular permeability	ISO	J:164563
Biological Process	GO:0006809	nitric oxide biosynthetic process	ISO	J:81494
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	ISO	J:155856
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IMP	J:182373
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IBA	J:265628
Biological Process	GO:0017014	protein nitrosylation	ISO	J:81494
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	IMP	J:182373