GO Annotations Graph

• Symbol: Dab2ip
• Name: disabled 2 interacting protein
• ID: MGI:1916851

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0005123	death receptor binding	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	ISO	J:164563
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:164563
Molecular Function	GO:0043548	phosphatidylinositol 3-kinase binding	ISO	J:164563
Molecular Function	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	ISO	J:164563
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ISO	J:164563
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:136554
Molecular Function	GO:0005515	protein binding	IPI	J:85094
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:136554
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:164563
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:164563
Molecular Function	GO:0035591	signaling adaptor activity	ISO	J:164563
Molecular Function	GO:0043184	vascular endothelial growth factor receptor 2 binding	ISO	J:164563
Cellular Component	GO:1990597	AIP1-IRE1 complex	IPI	J:136554
Cellular Component	GO:1990597	AIP1-IRE1 complex	ISO	J:164563
Cellular Component	GO:0030424	axon	IDA	J:195873
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0044300	cerebellar mossy fiber	IDA	J:195873
Cellular Component	GO:0044301	climbing fiber	IDA	J:195873
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:159941
Cellular Component	GO:0005737	cytoplasm	IDA	J:191935
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	IDA	J:195873
Cellular Component	GO:0032809	neuronal cell body membrane	IDA	J:191935
Cellular Component	GO:1990032	parallel fiber	IDA	J:195873
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:159941
Cellular Component	GO:0005886	plasma membrane	IDA	J:191935
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0021814	cell motility involved in cerebral cortex radial glia guided migration	IMP	J:191935
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:155856
Biological Process	GO:0071347	cellular response to interleukin-1	ISO	J:164563
Biological Process	GO:0071347	cellular response to interleukin-1	IDA	J:159941
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:159941
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IMP	J:154743
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IMP	J:136554
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	IDA	J:144734
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	ISO	J:164563
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	ISO	J:164563
Biological Process	GO:0007252	I-kappaB phosphorylation	IMP	J:159941
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:136554
Biological Process	GO:0021819	layer formation in cerebral cortex	IMP	J:191935
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:144734
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:157597
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010596	negative regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0010596	negative regulation of endothelial cell migration	IMP	J:144734
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0010633	negative regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:168268
Biological Process	GO:0070317	negative regulation of G0 to G1 transition	ISO	J:164563
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:159941
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity	ISO	J:164563
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IMP	J:144734
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity	IMP	J:154743
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	ISO	J:155856
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	IMP	J:144734
Biological Process	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	IDA	J:144734
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:191935
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:154743
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1900006	positive regulation of dendrite development	IMP	J:195873
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0043507	positive regulation of JUN kinase activity	ISO	J:164563
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IMP	J:136554
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:2001224	positive regulation of neuron migration	IMP	J:191935
Biological Process	GO:0010976	positive regulation of neuron projection development	IMP	J:191935
Biological Process	GO:1901800	positive regulation of proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0045732	positive regulation of protein catabolic process	IMP	J:159941
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IMP	J:154743
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IMP	J:157597
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0090129	positive regulation of synapse maturation	IMP	J:195873
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	ISO	J:164563
Biological Process	GO:0038026	reelin-mediated signaling pathway	IEA	J:72247
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0040008	regulation of growth	IEA	J:60000
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:159941
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:159941
Biological Process	GO:1900744	regulation of p38MAPK cascade	IMP	J:159941
Biological Process	GO:0043254	regulation of protein-containing complex assembly	IMP	J:159941
Biological Process	GO:0043254	regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0006986	response to unfolded protein	IEA	J:60000
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0035148	tube formation	ISO	J:164563
Biological Process	GO:0035148	tube formation	IMP	J:144734
Biological Process	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway	IMP	J:144734