GO Annotations Graph

• Symbol: Pxdn
• Name: peroxidasin
• ID: MGI:1916925

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	ISO	J:164563
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0020037	heme binding	ISO	J:164563
Molecular Function	GO:0043237	laminin-1 binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	ISO	J:164563
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IDA	J:320269
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IMP	J:291034
Molecular Function	GO:0004601	peroxidase activity	ISO	J:164563
Molecular Function	GO:0004601	peroxidase activity	IBA	J:265628
Cellular Component	GO:0005604	basement membrane	IDA	J:320269
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IDA	J:150789
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0070831	basement membrane assembly	IMP	J:291034
Biological Process	GO:0070831	basement membrane assembly	IDA	J:320269
Biological Process	GO:0070831	basement membrane assembly	ISO	J:164563
Biological Process	GO:0070831	basement membrane assembly	IMP	J:255484
Biological Process	GO:0071711	basement membrane organization	IMP	J:255314
Biological Process	GO:0071711	basement membrane organization	IMP	J:213336
Biological Process	GO:0007155	cell adhesion	IMP	J:213336
Biological Process	GO:0030199	collagen fibril organization	ISO	J:164563
Biological Process	GO:0030198	extracellular matrix organization	ISO	J:164563
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:150789
Biological Process	GO:0001654	eye development	IMP	J:285990
Biological Process	GO:0042744	hydrogen peroxide catabolic process	ISO	J:164563
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0070207	protein homotrimerization	ISO	J:164563
Biological Process	GO:0006979	response to oxidative stress	IEA	J:72247