GO Annotations Graph

• Symbol: Cad
• Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
• ID: MGI:1916969

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016597	amino acid binding	IEA	J:72247
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	ISO	J:155856
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	IBA	J:265628
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	IDA	J:307327
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	IDA	J:307327
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	ISO	J:73065
Molecular Function	GO:0005524	ATP binding	ISO	J:73065
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	ISO	J:155856
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	IMP	J:310328
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	IDA	J:307327
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	IMP	J:310328
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	IDA	J:307327
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	ISO	J:73065
Molecular Function	GO:0016743	carboxyl- or carbamoyltransferase activity	IEA	J:72247
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0004151	dihydroorotase activity	ISO	J:164563
Molecular Function	GO:0004151	dihydroorotase activity	ISO	J:155856
Molecular Function	GO:0004151	dihydroorotase activity	IBA	J:265628
Molecular Function	GO:0004151	dihydroorotase activity	IMP	J:310328
Molecular Function	GO:0004151	dihydroorotase activity	IMP	J:310328
Molecular Function	GO:0004151	dihydroorotase activity	ISO	J:73065
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEA	J:72247
Molecular Function	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	ISO	J:73065
Molecular Function	GO:0036094	small molecule binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0002134	UTP binding	ISO	J:73065
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0042995	cell projection	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:73065
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ISO	J:155856
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ISO	J:164563
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IBA	J:265628
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ISO	J:73065
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	ISO	J:307185
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	ISO	J:307185
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	IMP	J:310328
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	IMP	J:310328
Biological Process	GO:0006520	amino acid metabolic process	IEA	J:72247
Biological Process	GO:0019240	citrulline biosynthetic process	ISO	J:155856
Biological Process	GO:0019240	citrulline biosynthetic process	IBA	J:265628
Biological Process	GO:0006541	glutamine metabolic process	ISO	J:155856
Biological Process	GO:0006541	glutamine metabolic process	IBA	J:265628
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0006807	nitrogen compound metabolic process	IEA	J:72247
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	ISO	J:73065
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:73065
Biological Process	GO:0006221	pyrimidine nucleotide biosynthetic process	IEA	J:60000
Biological Process	GO:0032868	response to insulin	ISO	J:155856
Biological Process	GO:0042594	response to starvation	ISO	J:155856
Biological Process	GO:0006225	UDP biosynthetic process	ISO	J:307185
Biological Process	GO:0006228	UTP biosynthetic process	ISO	J:155856
Biological Process	GO:0006228	UTP biosynthetic process	IBA	J:265628
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:155856