GO Annotations Graph

• Symbol: Rnaseh2a
• Name: ribonuclease H2, large subunit
• ID: MGI:1916974

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004519	endonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0004523	RNA-DNA hybrid ribonuclease activity	ISO	J:164563
Molecular Function	GO:0004523	RNA-DNA hybrid ribonuclease activity	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0032299	ribonuclease H2 complex	IPI	J:161682
Cellular Component	GO:0032299	ribonuclease H2 complex	ISO	J:164563
Cellular Component	GO:0032299	ribonuclease H2 complex	IBA	J:265628
Cellular Component	GO:0032299	ribonuclease H2 complex	IDA	J:161682
Biological Process	GO:0043137	DNA replication, removal of RNA primer	IBA	J:265628
Biological Process	GO:0006298	mismatch repair	NAS	J:161682
Biological Process	GO:0006298	mismatch repair	IBA	J:265628
Biological Process	GO:0006298	mismatch repair	IMP	J:198961
Biological Process	GO:0006298	mismatch repair	ISO	J:198961
Biological Process	GO:0006401	RNA catabolic process	ISO	J:164563
Biological Process	GO:0016070	RNA metabolic process	IEA	J:72247