GO Annotations Graph

• Symbol: Card11
• Name: caspase recruitment domain family, member 11
• ID: MGI:1916978

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050700	CARD domain binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:84961
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Cellular Component	GO:0032449	CBM complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	IDA	J:205441
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2730893
Cellular Component	GO:0005886	plasma membrane	IDA	J:89322
Biological Process	GO:0030183	B cell differentiation	IMP	J:84036
Biological Process	GO:0042100	B cell proliferation	IMP	J:89322
Biological Process	GO:0042100	B cell proliferation	IMP	J:84036
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	IMP	J:89322
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:84036
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IMP	J:89322
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0002377	immunoglobulin production	IMP	J:84036
Biological Process	GO:0032623	interleukin-2 production	IMP	J:84036
Biological Process	GO:0032623	interleukin-2 production	IMP	J:89322
Biological Process	GO:0046649	lymphocyte activation	IMP	J:84036
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:89322
Biological Process	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	IMP	J:89322
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:304570
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:89322
Biological Process	GO:0032743	positive regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:0032743	positive regulation of interleukin-2 production	IMP	J:89322
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IMP	J:304570
Biological Process	GO:0050870	positive regulation of T cell activation	IMP	J:89322
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	IMP	J:304570
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0045577	regulation of B cell differentiation	IMP	J:89322
Biological Process	GO:0050776	regulation of immune response	IMP	J:89322
Biological Process	GO:0045580	regulation of T cell differentiation	IMP	J:89322
Biological Process	GO:0007165	signal transduction	IDA	J:84961
Biological Process	GO:0042110	T cell activation	IMP	J:89322
Biological Process	GO:0042110	T cell activation	IMP	J:84036
Biological Process	GO:0031295	T cell costimulation	ISO	J:164563
Biological Process	GO:0045061	thymic T cell selection	IMP	J:89322
Biological Process	GO:0038202	TORC1 signaling	ISO	J:164563