GO Annotations Graph

• Symbol: Fbxo7
• Name: F-box protein 7
• ID: MGI:1917004

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0019901	protein kinase binding	IPI	J:183053
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0097414	classical Lewy body	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0097409	glial cytoplasmic inclusion	ISO	J:164563
Cellular Component	GO:1990037	Lewy body core	ISO	J:164563
Cellular Component	GO:1990038	Lewy body corona	ISO	J:164563
Cellular Component	GO:0097462	Lewy neurite	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:226415
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:226415
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	ISO	J:164563
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:164563
Biological Process	GO:0000422	autophagy of mitochondrion	ISO	J:164563
Biological Process	GO:0030098	lymphocyte differentiation	IGI	J:183053
Biological Process	GO:0030098	lymphocyte differentiation	IMP	J:183053
Biological Process	GO:0030098	lymphocyte differentiation	IMP	J:183053
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	IMP	J:183053
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IMP	J:183053
Biological Process	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	ISO	J:164563
Biological Process	GO:0045620	negative regulation of lymphocyte differentiation	IMP	J:183053
Biological Process	GO:0045620	negative regulation of lymphocyte differentiation	IGI	J:183053
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	ISO	J:164563
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	IBA	J:265628
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	ISO	J:164563
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	ISO	J:155856
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	IBA	J:265628
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0070936	protein K48-linked ubiquitination	ISO	J:164563
Biological Process	GO:0006626	protein targeting to mitochondrion	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0040012	regulation of locomotion	ISO	J:164563
Biological Process	GO:0010975	regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563