GO Annotations Graph

• Symbol: Smc4
• Name: structural maintenance of chromosomes 4
• ID: MGI:1917349

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0003682	chromatin binding	IDA	J:195518
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:195518
Molecular Function	GO:0005515	protein binding	IPI	J:173441
Molecular Function	GO:0003697	single-stranded DNA binding	IDA	J:173441
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IEA	J:72247
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:240155
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:222181
Cellular Component	GO:0000796	condensin complex	ISO	J:164563
Cellular Component	GO:0000796	condensin complex	NAS	J:320052
Cellular Component	GO:0000796	condensin complex	TAS	J:222181
Cellular Component	GO:0000796	condensin complex	TAS	J:222181
Cellular Component	GO:0000796	condensin complex	TAS	J:222181
Cellular Component	GO:0000796	condensin complex	TAS	J:195518
Cellular Component	GO:0000796	condensin complex	IDA	J:183026
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	TAS	J:173441
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0030261	chromosome condensation	IEA	J:60000
Biological Process	GO:0051276	chromosome organization	IEA	J:72247
Biological Process	GO:0051383	kinetochore organization	IMP	J:183026
Biological Process	GO:0010032	meiotic chromosome condensation	IMP	J:183026
Biological Process	GO:0045132	meiotic chromosome segregation	IMP	J:183026
Biological Process	GO:0007076	mitotic chromosome condensation	ISO	J:164563
Biological Process	GO:1905821	positive regulation of chromosome condensation	ISO	J:164563
Biological Process	GO:0051984	positive regulation of chromosome segregation	IMP	J:222181
Biological Process	GO:1905820	positive regulation of chromosome separation	IMP	J:183026
Biological Process	GO:0000012	single strand break repair	TAS	J:173441