GO Annotations Graph

• Symbol: Plscr3
• Name: phospholipid scramblase 3
• ID: MGI:1917560

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0032791	lead ion binding	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0045340	mercury ion binding	ISO	J:164563
Molecular Function	GO:0017128	phospholipid scramblase activity	ISO	J:164563
Molecular Function	GO:0017128	phospholipid scramblase activity	ISO	J:155856
Molecular Function	GO:0017128	phospholipid scramblase activity	IBA	J:265628
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IDA	J:289458
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:289458
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IMP	J:289458
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0032049	cardiolipin biosynthetic process	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IEP	J:127023
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:92404
Biological Process	GO:0042593	glucose homeostasis	IMP	J:92404
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	IBA	J:265628
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0090199	regulation of release of cytochrome c from mitochondria	ISO	J:164563