GO Annotations Graph

• Symbol: Prdm16
• Name: PR domain containing 16
• ID: MGI:1917923

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:251809
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IDA	J:269562
Molecular Function	GO:0140948	histone H3K9 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:207678
Molecular Function	GO:0005515	protein binding	IPI	J:153416
Molecular Function	GO:0005515	protein binding	IPI	J:152000
Molecular Function	GO:0005515	protein binding	IPI	J:153416
Molecular Function	GO:0005515	protein binding	IPI	J:129891
Molecular Function	GO:0005515	protein binding	IPI	J:122807
Molecular Function	GO:0005515	protein binding	IPI	J:138823
Molecular Function	GO:0005515	protein binding	IPI	J:129891
Molecular Function	GO:0005515	protein binding	IPI	J:251809
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:129891
Molecular Function	GO:0046332	SMAD binding	IPI	J:122807
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:129891
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:138823
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0016235	aggresome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:153416
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IC	J:251809
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:153416
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:153416
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:152000
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:138823
Biological Process	GO:0050873	brown fat cell differentiation	IMP	J:129891
Biological Process	GO:0050873	brown fat cell differentiation	IMP	J:213153
Biological Process	GO:0050873	brown fat cell differentiation	IMP	J:213153
Biological Process	GO:0048468	cell development	IC	J:213153
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0070828	heterochromatin organization	IMP	J:269562
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:153416
Biological Process	GO:0030853	negative regulation of granulocyte differentiation	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:213153
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IMP	J:157112
Biological Process	GO:0022008	neurogenesis	IDA	J:144373
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	IMP	J:213153
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	IMP	J:213153
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:213153
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:208683
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:152000
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:153416
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:251809
Biological Process	GO:0043457	regulation of cellular respiration	IDA	J:153416
Biological Process	GO:0043457	regulation of cellular respiration	IDA	J:129891
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060021	roof of mouth development	IMP	J:157112
Biological Process	GO:0035019	somatic stem cell population maintenance	IDA	J:150463
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:213153
Biological Process	GO:0019827	stem cell population maintenance	IGI	J:213153
Biological Process	GO:0043586	tongue development	IMP	J:157112
Biological Process	GO:0050872	white fat cell differentiation	IDA	J:153416