GO Annotations Graph

• Symbol: Setd2
• Name: SET domain containing 2
• ID: MGI:1918177

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	ISO	J:164563
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IMP	J:243534
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IMP	J:203796
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IMP	J:157570
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IMP	J:130872
Molecular Function	GO:0140955	histone H3K36 trimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IDA	J:130872
Cellular Component	GO:0005694	chromosome	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:130872
Cellular Component	GO:0005634	nucleus	IDA	J:106641
Biological Process	GO:0001525	angiogenesis	IMP	J:157570
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0035441	cell migration involved in vasculogenesis	IMP	J:157570
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0060977	coronary vasculature morphogenesis	IMP	J:157570
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	IMP	J:157570
Biological Process	GO:0048568	embryonic organ development	IMP	J:157570
Biological Process	GO:0060669	embryonic placenta morphogenesis	IMP	J:157570
Biological Process	GO:0035987	endodermal cell differentiation	IMP	J:243534
Biological Process	GO:0030900	forebrain development	IMP	J:157570
Biological Process	GO:0097676	histone H3-K36 dimethylation	ISO	J:164563
Biological Process	GO:0010452	histone H3-K36 methylation	IEA	J:72247
Biological Process	GO:0097198	histone H3-K36 trimethylation	ISO	J:164563
Biological Process	GO:0097198	histone H3-K36 trimethylation	IBA	J:265628
Biological Process	GO:0034968	histone lysine methylation	IEA	J:72247
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0048332	mesoderm morphogenesis	IMP	J:157570
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:1902850	microtubule cytoskeleton organization involved in mitosis	ISO	J:164563
Biological Process	GO:0006298	mismatch repair	ISO	J:164563
Biological Process	GO:0001763	morphogenesis of a branching structure	IMP	J:157570
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0001843	neural tube closure	IMP	J:157570
Biological Process	GO:0034728	nucleosome organization	ISO	J:164563
Biological Process	GO:0018023	peptidyl-lysine trimethylation	ISO	J:164563
Biological Process	GO:0018023	peptidyl-lysine trimethylation	IMP	J:130872
Biological Process	GO:0018023	peptidyl-lysine trimethylation	IMP	J:157570
Biological Process	GO:0060039	pericardium development	IMP	J:157570
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0032727	positive regulation of interferon-alpha production	ISO	J:164563
Biological Process	GO:0045778	positive regulation of ossification	ISO	J:155856
Biological Process	GO:0032465	regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0010468	regulation of gene expression	IMP	J:157570
Biological Process	GO:0010793	regulation of mRNA export from nucleus	ISO	J:164563
Biological Process	GO:1905634	regulation of protein localization to chromatin	ISO	J:164563
Biological Process	GO:0034340	response to type I interferon	ISO	J:164563
Biological Process	GO:0048864	stem cell development	IMP	J:157570
Biological Process	GO:0048863	stem cell differentiation	IMP	J:243534
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0001570	vasculogenesis	IMP	J:157570