GO Annotations Graph

• Symbol: Gpr39
• Name: G protein-coupled receptor 39
• ID: MGI:1918361

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IMP	J:228528
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0008343	adult feeding behavior	IMP	J:124913
Biological Process	GO:0071294	cellular response to zinc ion	IMP	J:192254
Biological Process	GO:0071294	cellular response to zinc ion	IMP	J:228528
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:124913
Biological Process	GO:0002024	diet induced thermogenesis	IMP	J:178419
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:192254
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:151806
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0001696	gastric acid secretion	IMP	J:124913
Biological Process	GO:0035483	gastric emptying	IMP	J:124913
Biological Process	GO:0042593	glucose homeostasis	IMP	J:178419
Biological Process	GO:0042593	glucose homeostasis	IMP	J:158062
Biological Process	GO:0030073	insulin secretion	IMP	J:151806
Biological Process	GO:0030073	insulin secretion	IMP	J:151806
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	IMP	J:158062
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	IMP	J:158062
Biological Process	GO:0060455	negative regulation of gastric acid secretion	IMP	J:124913
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:228528
Biological Process	GO:0032024	positive regulation of insulin secretion	IMP	J:151806
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	IMP	J:158062
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IMP	J:228528
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	IMP	J:192254
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	IMP	J:228528
Biological Process	GO:0030641	regulation of cellular pH	IMP	J:228528
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:178419
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:192254
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:192254
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	IMP	J:192254
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	IMP	J:192254
Biological Process	GO:0007165	signal transduction	IEA	J:60000