GO Annotations Graph

• Symbol: Ifih1
• Name: interferon induced with helicase C domain 1
• ID: MGI:1918836

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0032559	adenyl ribonucleotide binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	IBA	J:265628
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0038187	pattern recognition receptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:193402
Molecular Function	GO:0005515	protein binding	IPI	J:175771
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:240099
Molecular Function	GO:0035639	purine ribonucleoside triphosphate binding	ISO	J:164563
Molecular Function	GO:0043021	ribonucleoprotein complex binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003724	RNA helicase activity	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:240099
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0140374	antiviral innate immune response	IBA	J:265628
Biological Process	GO:0140374	antiviral innate immune response	IMP	J:240099
Biological Process	GO:0071360	cellular response to exogenous dsRNA	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IMP	J:183219
Biological Process	GO:0032608	interferon-beta production	IMP	J:240099
Biological Process	GO:0039530	MDA-5 signaling pathway	ISO	J:164563
Biological Process	GO:0039530	MDA-5 signaling pathway	IBA	J:265628
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0032727	positive regulation of interferon-alpha production	ISO	J:164563
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0060760	positive regulation of response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0051259	protein complex oligomerization	IDA	J:240099
Biological Process	GO:0016925	protein sumoylation	ISO	J:164563
Biological Process	GO:0009615	response to virus	ISO	J:164563
Biological Process	GO:0009615	response to virus	IMP	J:183219
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IMP	J:240099