GO Annotations Graph

• Symbol: Shtn1
• Name: shootin 1
• ID: MGI:1918903

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0019894	kinesin binding	IPI	J:199805
Molecular Function	GO:0005515	protein binding	IPI	J:195805
Cellular Component	GO:0030424	axon	IDA	J:199805
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0044295	axonal growth cone	IBA	J:265628
Cellular Component	GO:0044295	axonal growth cone	IDA	J:195805
Cellular Component	GO:0031252	cell leading edge	IDA	J:199805
Cellular Component	GO:0031252	cell leading edge	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0030426	growth cone	IDA	J:199805
Cellular Component	GO:0030426	growth cone	ISO	J:115005
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0005874	microtubule	ISO	J:195805
Cellular Component	GO:0005875	microtubule associated complex	IDA	J:199805
Cellular Component	GO:0015630	microtubule cytoskeleton	IDA	J:199805
Cellular Component	GO:0043204	perikaryon	IDA	J:199805
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:199805
Biological Process	GO:0061573	actin filament bundle retrograde transport	ISO	J:155856
Biological Process	GO:0007409	axonogenesis	ISO	J:155856
Biological Process	GO:0007409	axonogenesis	ISO	J:73065
Biological Process	GO:0032488	Cdc42 protein signal transduction	ISO	J:155856
Biological Process	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	ISO	J:155856
Biological Process	GO:0061163	endoplasmic reticulum polarization	IMP	J:199805
Biological Process	GO:0051899	membrane depolarization	ISO	J:115005
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0038007	netrin-activated signaling pathway	ISO	J:155856
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:199805
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0045773	positive regulation of axon extension	ISO	J:155856
Biological Process	GO:2001224	positive regulation of neuron migration	IMP	J:199805
Biological Process	GO:2001224	positive regulation of neuron migration	ISO	J:164563
Biological Process	GO:2001224	positive regulation of neuron migration	IBA	J:265628
Biological Process	GO:0007265	Ras protein signal transduction	ISO	J:155856
Biological Process	GO:2000114	regulation of establishment of cell polarity	IMP	J:199805
Biological Process	GO:2000114	regulation of establishment of cell polarity	IGI	J:195805
Biological Process	GO:2001222	regulation of neuron migration	IGI	J:195805
Biological Process	GO:0006930	substrate-dependent cell migration, cell extension	ISO	J:155856