GO Annotations Graph

• Symbol: Telo2
• Name: telomere maintenance 2
• ID: MGI:1918968

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:164563
Molecular Function	GO:0051879	Hsp90 protein binding	IBA	J:265628
Molecular Function	GO:0019900	kinase binding	ISO	J:212482
Molecular Function	GO:0060090	molecular adaptor activity	IMP	J:165255
Molecular Function	GO:0005515	protein binding	IPI	J:165255
Molecular Function	GO:0005515	protein binding	IPI	J:245365
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:73065
Molecular Function	GO:0044877	protein-containing complex binding	IDA	J:165255
Molecular Function	GO:0140777	protein-containing complex stabilizing activity	ISO	J:212482
Molecular Function	GO:0042162	telomeric DNA binding	IBA	J:265628
Cellular Component	GO:0070209	ASTRA complex	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0034399	nuclear periphery	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0031931	TORC1 complex	ISO	J:164563
Cellular Component	GO:0031932	TORC2 complex	ISO	J:164563
Cellular Component	GO:0110078	TTT complex	ISO	J:164563
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:1904263	positive regulation of TORC1 signaling	ISO	J:164563
Biological Process	GO:1904515	positive regulation of TORC2 signaling	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	IMP	J:165255
Biological Process	GO:0050821	protein stabilization	IBA	J:265628
Biological Process	GO:0050821	protein stabilization	ISO	J:212482
Biological Process	GO:0032006	regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	IBA	J:265628