GO Annotations Graph

• Symbol: Pla2g4e
• Name: phospholipase A2, group IVE
• ID: MGI:1919144

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	IBA	J:265628
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016410	N-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0016410	N-acyltransferase activity	IDA	J:287058
Molecular Function	GO:0016410	N-acyltransferase activity	IDA	J:262289
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	IDA	J:287045
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	IDA	J:287045
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	IDA	J:287045
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	IDA	J:287045
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	IDA	J:287045
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	IDA	J:287045
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	IDA	J:287045
Molecular Function	GO:0004623	phospholipase A2 activity	IDA	J:100848
Molecular Function	GO:0004620	phospholipase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:100848
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0031901	early endosome membrane	IDA	J:287045
Cellular Component	GO:0031901	early endosome membrane	IDA	J:262289
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:262289
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:262289
Cellular Component	GO:0005886	plasma membrane	IDA	J:287045
Biological Process	GO:0046475	glycerophospholipid catabolic process	IBA	J:265628
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0070292	N-acylphosphatidylethanolamine metabolic process	IDA	J:287058
Biological Process	GO:0070292	N-acylphosphatidylethanolamine metabolic process	IDA	J:262289
Biological Process	GO:0070292	N-acylphosphatidylethanolamine metabolic process	ISO	J:164563
Biological Process	GO:0009395	phospholipid catabolic process	IEA	J:72247
Biological Process	GO:2001137	positive regulation of endocytic recycling	ISO	J:164563
Biological Process	GO:2001137	positive regulation of endocytic recycling	IMP	J:287045