GO Annotations Graph

• Symbol: Sulf2
• Name: sulfatase 2
• ID: MGI:1919293

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004065	arylsulfatase activity	ISO	J:164563
Molecular Function	GO:0004065	arylsulfatase activity	ISO	J:80928
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005539	glycosaminoglycan binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	ISO	J:164563
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	IMP	J:180455
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	IBA	J:265628
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	ISO	J:80928
Molecular Function	GO:0008484	sulfuric ester hydrolase activity	IEA	J:72247
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:80928
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:72247
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:180645
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0060348	bone development	IGI	J:129305
Biological Process	GO:0051216	cartilage development	IMP	J:180554
Biological Process	GO:0002063	chondrocyte development	IMP	J:180554
Biological Process	GO:0048706	embryonic skeletal system development	IGI	J:130163
Biological Process	GO:0014846	esophagus smooth muscle contraction	IGI	J:124898
Biological Process	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	IDA	J:124898
Biological Process	GO:0032836	glomerular basement membrane development	IGI	J:180645
Biological Process	GO:0003094	glomerular filtration	IGI	J:180645
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	ISO	J:164563
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	IMP	J:180455
Biological Process	GO:0060384	innervation	IGI	J:124898
Biological Process	GO:0001822	kidney development	IGI	J:129305
Biological Process	GO:0097421	liver regeneration	IMP	J:201786
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	IGI	J:180645
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	IGI	J:129305
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:201786
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	IGI	J:180645
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:2000345	regulation of hepatocyte proliferation	IMP	J:201786
Biological Process	GO:0009611	response to wounding	IMP	J:201786
Biological Process	GO:0006790	sulfur compound metabolic process	ISO	J:80928