GO Annotations Graph

• Symbol: Ush1c
• Name: USH1 protein network component harmonin
• ID: MGI:1919338

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	IEA	J:72247
Molecular Function	GO:0032029	myosin tail binding	ISO	J:199579
Molecular Function	GO:0005515	protein binding	IPI	J:106804
Molecular Function	GO:0005515	protein binding	IPI	J:99757
Molecular Function	GO:0005515	protein binding	IPI	J:186070
Molecular Function	GO:0005515	protein binding	IPI	J:95929
Molecular Function	GO:0005515	protein binding	IPI	J:80836
Molecular Function	GO:0005515	protein binding	IPI	J:95929
Molecular Function	GO:0005515	protein binding	IPI	J:95929
Molecular Function	GO:0005515	protein binding	IPI	J:82099
Molecular Function	GO:0005515	protein binding	IPI	J:105750
Molecular Function	GO:0005515	protein binding	IPI	J:80836
Molecular Function	GO:0005515	protein binding	IPI	J:95929
Molecular Function	GO:0030507	spectrin binding	ISO	J:199579
Cellular Component	GO:0045177	apical part of cell	ISO	J:164563
Cellular Component	GO:0005903	brush border	IDA	J:212327
Cellular Component	GO:0005903	brush border	ISO	J:164563
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0005902	microvillus	ISO	J:164563
Cellular Component	GO:0005902	microvillus	IDA	J:212327
Cellular Component	GO:0001917	photoreceptor inner segment	ISO	J:155856
Cellular Component	GO:0001917	photoreceptor inner segment	IBA	J:265628
Cellular Component	GO:0001917	photoreceptor inner segment	IDA	J:86248
Cellular Component	GO:0001917	photoreceptor inner segment	IDA	J:132040
Cellular Component	GO:0001750	photoreceptor outer segment	ISO	J:155856
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:86248
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:132040
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:82099
Cellular Component	GO:0005886	plasma membrane	IDA	J:82099
Cellular Component	GO:0005886	plasma membrane	IDA	J:82099
Cellular Component	GO:0005886	plasma membrane	IDA	J:82099
Cellular Component	GO:0005886	plasma membrane	IDA	J:82099
Cellular Component	GO:0005886	plasma membrane	IDA	J:82099
Cellular Component	GO:0002142	stereocilia ankle link complex	IBA	J:265628
Cellular Component	GO:0032420	stereocilium	ISO	J:155856
Cellular Component	GO:0032420	stereocilium	EXP	J:230827
Cellular Component	GO:0032420	stereocilium	IDA	J:80836
Cellular Component	GO:0032420	stereocilium	IDA	J:80836
Cellular Component	GO:0032420	stereocilium	IDA	J:80836
Cellular Component	GO:0032420	stereocilium	IDA	J:157099
Cellular Component	GO:0032420	stereocilium	IDA	J:80836
Cellular Component	GO:0032420	stereocilium	IDA	J:80836
Cellular Component	GO:0032420	stereocilium	IDA	J:80836
Cellular Component	GO:0032426	stereocilium tip	IBA	J:265628
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:86248
Cellular Component	GO:1990435	upper tip-link density	IDA	J:283627
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:80836
Biological Process	GO:1904970	brush border assembly	IMP	J:212327
Biological Process	GO:1904970	brush border assembly	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0050957	equilibrioception	ISO	J:164563
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IBA	J:265628
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:85400
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:85400
Biological Process	GO:0042472	inner ear morphogenesis	IBA	J:265628
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:85400
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:85400
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IBA	J:265628
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IMP	J:135991
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:85400
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:85400
Biological Process	GO:0030046	parallel actin filament bundle assembly	IDA	J:80836
Biological Process	GO:0045494	photoreceptor cell maintenance	ISO	J:164563
Biological Process	GO:1904106	protein localization to microvillus	ISO	J:164563
Biological Process	GO:1904106	protein localization to microvillus	IMP	J:212327
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0032532	regulation of microvillus length	IMP	J:212327
Biological Process	GO:0046549	retinal cone cell development	IBA	J:265628
Biological Process	GO:0050953	sensory perception of light stimulus	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	IMP	J:85400
Biological Process	GO:0007605	sensory perception of sound	IMP	J:85400