GO Annotations Graph

• Symbol: Tpx2
• Name: TPX2, microtubule-associated
• ID: MGI:1919369

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061676	importin-alpha family protein binding	IDA	J:224841
Molecular Function	GO:0061676	importin-alpha family protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:319955
Molecular Function	GO:0005515	protein binding	IPI	J:158132
Molecular Function	GO:0019901	protein kinase binding	IPI	J:161103
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:73065
Cellular Component	GO:0005818	aster	ISO	J:73065
Cellular Component	GO:0043203	axon hillock	IDA	J:158132
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0045171	intercellular bridge	ISO	J:164563
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0005874	microtubule	IEA	J:72247
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:73065
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005819	spindle	IDA	J:161103
Cellular Component	GO:0005819	spindle	IDA	J:319955
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0007020	microtubule nucleation	ISO	J:164563
Biological Process	GO:0090307	mitotic spindle assembly	IMP	J:224841
Biological Process	GO:0090307	mitotic spindle assembly	ISO	J:164563
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	ISO	J:164563
Biological Process	GO:0060236	regulation of mitotic spindle organization	IMP	J:161103
Biological Process	GO:0051225	spindle assembly	ISO	J:73065