GO Annotations Graph

• Symbol: Zbtb46
• Name: zinc finger and BTB domain containing 46
• ID: MGI:1919397

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:191314
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200482
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:191314
Cellular Component	GO:0000785	chromatin	IDA	J:191314
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0097028	dendritic cell differentiation	IMP	J:184205
Biological Process	GO:0097028	dendritic cell differentiation	IMP	J:184205
Biological Process	GO:0030851	granulocyte differentiation	IMP	J:184205
Biological Process	GO:0030225	macrophage differentiation	IMP	J:184205
Biological Process	GO:2001199	negative regulation of dendritic cell differentiation	IMP	J:184205
Biological Process	GO:0030853	negative regulation of granulocyte differentiation	IMP	J:184205
Biological Process	GO:0002695	negative regulation of leukocyte activation	IMP	J:184205
Biological Process	GO:0045650	negative regulation of macrophage differentiation	IMP	J:184205
Biological Process	GO:0045656	negative regulation of monocyte differentiation	IMP	J:184205
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:191314
Biological Process	GO:0002273	plasmacytoid dendritic cell differentiation	IMP	J:184205
Biological Process	GO:2001200	positive regulation of dendritic cell differentiation	IMP	J:184205
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563