GO Annotations Graph

• Symbol: Fbxl2
• Name: F-box and leucine-rich repeat protein 2
• ID: MGI:1919429

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:172833
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	IDA	J:196439
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	ISO	J:164563
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	IBA	J:265628
Biological Process	GO:0044830	modulation by host of viral RNA genome replication	ISO	J:164563
Biological Process	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	ISO	J:164563
Biological Process	GO:0006513	protein monoubiquitination	IGI	J:172833
Biological Process	GO:0006513	protein monoubiquitination	IMP	J:172833
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0010506	regulation of autophagy	ISO	J:164563
Biological Process	GO:0050727	regulation of inflammatory response	IDA	J:196439
Biological Process	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IDA	J:196439
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IMP	J:172833