GO Annotations Graph

• Symbol: Tbc1d5
• Name: TBC1 domain family, member 5
• ID: MGI:1919488

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035612	AP-2 adaptor complex binding	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:1905394	retromer complex binding	ISO	J:164563
Cellular Component	GO:0030122	AP-2 adaptor complex	ISO	J:164563
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	ISO	J:164563
Cellular Component	GO:0005776	autophagosome	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030904	retromer complex	ISO	J:73065
Biological Process	GO:0090630	activation of GTPase activity	IBA	J:265628
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0016236	macroautophagy	ISO	J:164563
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0042594	response to starvation	ISO	J:164563
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	ISO	J:164563