GO Annotations Graph

• Symbol: Brf1
• Name: BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
• ID: MGI:1919558

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000995	RNA polymerase III general transcription initiation factor activity	IBA	J:265628
Molecular Function	GO:0001006	RNA polymerase III type 3 promoter sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0017025	TBP-class protein binding	IEA	J:72247
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0000126	transcription factor TFIIIB complex	IBA	J:265628
Cellular Component	GO:0097550	transcription preinitiation complex	IBA	J:265628
Biological Process	GO:0006352	DNA-templated transcription initiation	IBA	J:265628
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	ISO	J:155856
Biological Process	GO:0043488	regulation of mRNA stability	IMP	J:88901
Biological Process	GO:0006383	transcription by RNA polymerase III	IBA	J:265628
Biological Process	GO:0070897	transcription preinitiation complex assembly	IEA	J:72247