GO Annotations Graph

• Symbol: Tmem175
• Name: transmembrane protein 175
• ID: MGI:1919642

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050544	arachidonic acid binding	ISO	J:164563
Molecular Function	GO:0005267	potassium channel activity	ISO	J:164563
Molecular Function	GO:0022841	potassium ion leak channel activity	ISO	J:164563
Molecular Function	GO:0022841	potassium ion leak channel activity	IMP	J:225577
Molecular Function	GO:0022841	potassium ion leak channel activity	IBA	J:265628
Molecular Function	GO:0015252	proton channel activity	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0035752	lysosomal lumen pH elevation	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:304120
Biological Process	GO:0090385	phagosome-lysosome fusion	IMP	J:225577
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:225577
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:0035751	regulation of lysosomal lumen pH	ISO	J:164563
Biological Process	GO:0035751	regulation of lysosomal lumen pH	IMP	J:225577