GO Annotations Graph

• Symbol: Pinx1
• Name: PIN2/TERF1 interacting, telomerase inhibitor 1
• ID: MGI:1919650

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0010521	telomerase inhibitor activity	ISO	J:164563
Molecular Function	GO:0010521	telomerase inhibitor activity	IBA	J:265628
Molecular Function	GO:0070034	telomerase RNA binding	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:72504
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0000228	nuclear chromosome	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:72504
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005819	spindle	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0031397	negative regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0051974	negative regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:1904751	positive regulation of protein localization to nucleolus	ISO	J:164563
Biological Process	GO:1904744	positive regulation of telomeric DNA binding	ISO	J:164563
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	ISO	J:164563
Biological Process	GO:1902570	protein localization to nucleolus	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	ISO	J:72504