GO Annotations Graph

• Symbol: Uaca
• Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
• ID: MGI:1919815

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:222141
Molecular Function	GO:0005515	protein binding	IPI	J:89918
Molecular Function	GO:0005515	protein binding	IPI	J:89918
Cellular Component	GO:0043293	apoptosome	IDA	J:93333
Cellular Component	GO:0005737	cytoplasm	IDA	J:89918
Cellular Component	GO:0005737	cytoplasm	IDA	J:84854
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6804642
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:93333
Cellular Component	GO:0016020	membrane	IDA	J:84854
Cellular Component	GO:0005635	nuclear envelope	IDA	J:84854
Cellular Component	GO:0005635	nuclear envelope	IDA	J:89918
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:93333
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:93333
Biological Process	GO:0097190	apoptotic signaling pathway	IEA	J:72247
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:93333
Biological Process	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	IMP	J:93333
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:89918
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	IMP	J:89918
Biological Process	GO:0038061	NIK/NF-kappaB signaling	IMP	J:89918
Biological Process	GO:0043065	positive regulation of apoptotic process	IDA	J:93333
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:89918
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:93333
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:93333
Biological Process	GO:0042307	positive regulation of protein import into nucleus	IMP	J:93333
Biological Process	GO:0006606	protein import into nucleus	IMP	J:93333
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	IEA	J:72247
Biological Process	GO:0009411	response to UV	IMP	J:93333