GO Annotations Graph

• Symbol: Hpf1
• Name: histone PARylation factor 1
• ID: MGI:1919862

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0072572	poly-ADP-D-ribose binding	IBA	J:265628
Molecular Function	GO:0140768	protein ADP-ribosyltransferase-substrate adaptor activity	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IBA	J:265628
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0140861	DNA repair-dependent chromatin remodeling	ISO	J:164563
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0031056	regulation of histone modification	ISO	J:164563
Biological Process	GO:0010835	regulation of protein ADP-ribosylation	ISO	J:164563
Biological Process	GO:0010835	regulation of protein ADP-ribosylation	IBA	J:265628