GO Annotations Graph

• Symbol: Tppp
• Name: tubulin polymerization promoting protein
• ID: MGI:1920198

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140490	microtubule nucleator activity	ISO	J:164563
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0046983	protein dimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:153311
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005874	microtubule	IDA	J:153311
Cellular Component	GO:0005874	microtubule	IBA	J:265628
Cellular Component	GO:0097427	microtubule bundle	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005634	nucleus	IDA	J:153311
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0150051	postsynaptic Golgi apparatus	ISO	J:155856
Biological Process	GO:0030953	astral microtubule organization	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0001578	microtubule bundle formation	ISO	J:164563
Biological Process	GO:0001578	microtubule bundle formation	IBA	J:265628
Biological Process	GO:0051418	microtubule nucleation by microtubule organizing center	ISO	J:164563
Biological Process	GO:0046785	microtubule polymerization	ISO	J:164563
Biological Process	GO:0046785	microtubule polymerization	IDA	J:153311
Biological Process	GO:0046785	microtubule polymerization	IBA	J:265628
Biological Process	GO:0032288	myelin assembly	IMP	J:279928
Biological Process	GO:0032288	myelin assembly	ISO	J:155856
Biological Process	GO:1904428	negative regulation of tubulin deacetylation	ISO	J:164563
Biological Process	GO:0014003	oligodendrocyte development	IMP	J:279928
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:279928
Biological Process	GO:0031643	positive regulation of myelination	IMP	J:279928
Biological Process	GO:0031643	positive regulation of myelination	ISO	J:155856
Biological Process	GO:0032273	positive regulation of protein polymerization	ISO	J:164563
Biological Process	GO:0032273	positive regulation of protein polymerization	IBA	J:265628
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	ISO	J:164563