GO Annotations Graph

• Symbol: Dact2
• Name: dishevelled-binding antagonist of beta-catenin 2
• ID: MGI:1920347

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	IDA	J:187547
Molecular Function	GO:0070097	delta-catenin binding	IDA	J:187547
Molecular Function	GO:0005515	protein binding	IPI	J:187547
Molecular Function	GO:0051018	protein kinase A binding	IDA	J:187547
Molecular Function	GO:0005080	protein kinase C binding	IDA	J:187547
Molecular Function	GO:0008134	transcription factor binding	IDA	J:187547
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Biological Process	GO:0003382	epithelial cell morphogenesis	IMP	J:164447
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IGI	J:202604
Biological Process	GO:0072061	inner medullary collecting duct development	IMP	J:164447
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007162	negative regulation of cell adhesion	IMP	J:139684
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	IMP	J:139684
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	IDA	J:187575
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	IBA	J:265628
Biological Process	GO:0043588	skin development	IMP	J:139684