GO Annotations Graph

• Symbol: Wasl
• Name: WASP like actin nucleation promoting factor
• ID: MGI:1920428

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:189997
Molecular Function	GO:0005515	protein binding	IPI	J:269545
Molecular Function	GO:0005515	protein binding	IPI	J:172000
Molecular Function	GO:0005515	protein binding	IPI	J:283192
Molecular Function	GO:0005515	protein binding	IPI	J:245353
Molecular Function	GO:0005515	protein binding	IPI	J:91030
Molecular Function	GO:0005515	protein binding	IPI	J:93351
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:169571
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Cellular Component	GO:0030478	actin cap	IDA	J:176957
Cellular Component	GO:0031252	cell leading edge	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IC	J:73609
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-3928605
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-3928643
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-442572
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:239194
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:239194
Cellular Component	GO:0000139	Golgi membrane	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IDA	J:91137
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:176957
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0030041	actin filament polymerization	ISO	J:164563
Biological Process	GO:0045010	actin nucleation	TAS	J:73609
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0060997	dendritic spine morphogenesis	IMP	J:239194
Biological Process	GO:0010324	membrane invagination	ISO	J:155856
Biological Process	GO:2000402	negative regulation of lymphocyte migration	ISO	J:164563
Biological Process	GO:1903526	negative regulation of membrane tubulation	ISO	J:164563
Biological Process	GO:0097320	plasma membrane tubulation	ISO	J:155856
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	IEA	J:72247
Biological Process	GO:0050921	positive regulation of chemotaxis	ISO	J:155856
Biological Process	GO:2000370	positive regulation of clathrin-dependent endocytosis	ISO	J:155856
Biological Process	GO:0051491	positive regulation of filopodium assembly	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0099173	postsynapse organization	ISO	J:155856
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0031503	protein-containing complex localization	IMP	J:176957
Biological Process	GO:0060491	regulation of cell projection assembly	ISO	J:155856
Biological Process	GO:0099175	regulation of postsynapse organization	IMP	J:239194
Biological Process	GO:0099175	regulation of postsynapse organization	IDA	J:239194
Biological Process	GO:0032880	regulation of protein localization	IMP	J:190527
Biological Process	GO:0009617	response to bacterium	IMP	J:73609
Biological Process	GO:0051653	spindle localization	IMP	J:176957
Biological Process	GO:0006900	vesicle budding from membrane	ISO	J:155856
Biological Process	GO:0016050	vesicle organization	ISO	J:155856
Biological Process	GO:0030050	vesicle transport along actin filament	ISO	J:155856