Nfatc4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nfatc4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
MGI:1920431

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:177735
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:83794
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:121372
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:108648
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:177735
Molecular Function	GO:0005515	protein binding	IPI	J:177735
Molecular Function	GO:0005515	protein binding	IPI	J:177735
Molecular Function	GO:0005515	protein binding	IPI	J:162572
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:108648
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:83794
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:121372
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	IBA	J:265628
Molecular Function	GO:0008134	transcription factor binding	IDA	J:144171
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:184759
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:111735
Cellular Component	GO:0005829	cytosol	IDA	J:133209
Cellular Component	GO:0005829	cytosol	IDA	J:121372
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:184759
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:111735
Cellular Component	GO:0005634	nucleus	IDA	J:121372
Cellular Component	GO:0005634	nucleus	IDA	J:70266
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:70266
Cellular Component	GO:0005634	nucleus	IDA	J:133209
Cellular Component	GO:0005634	nucleus	IDA	J:70266
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:162572
Biological Process	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	IMP	J:184759
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:70266
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:70266
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IBA	J:265628
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IGI	J:144171
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0045333	cellular respiration	IDA	J:84138
Biological Process	GO:1904637	cellular response to ionomycin	ISO	J:155856
Biological Process	GO:0071285	cellular response to lithium ion	IDA	J:163720
Biological Process	GO:0034644	cellular response to UV	IGI	J:121372
Biological Process	GO:0001816	cytokine production	IBA	J:265628
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:194263
Biological Process	GO:0007507	heart development	IGI	J:121907
Biological Process	GO:0007507	heart development	IGI	J:84138
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:121372
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IGI	J:121372
Biological Process	GO:0007616	long-term memory	IMP	J:184759
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:184759
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0035562	negative regulation of chromatin binding	IDA	J:194263
Biological Process	GO:0050774	negative regulation of dendrite morphogenesis	IMP	J:194263
Biological Process	GO:1902894	negative regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:184759
Biological Process	GO:0032091	negative regulation of protein binding	IDA	J:177735
Biological Process	GO:0032091	negative regulation of protein binding	IDA	J:177735
Biological Process	GO:2000297	negative regulation of synapse maturation	IMP	J:194263
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:177735
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:108648
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IDA	J:177735
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:133209
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IMP	J:163720
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:133209
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:144171
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:111735
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:162572
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:144171
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:133209
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:123002
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:111735
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:121372
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:121372
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:83794
Biological Process	GO:0048167	regulation of synaptic plasticity	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060074	synapse maturation	IMP	J:194263
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:121372
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:133209
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:133209
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:121372
Biological Process	GO:0097084	vascular associated smooth muscle cell development	IGI	J:70266
Biological Process	GO:0097084	vascular associated smooth muscle cell development	IGI	J:70266
Biological Process	GO:0035886	vascular associated smooth muscle cell differentiation	IGI	J:70266
Biological Process	GO:0035886	vascular associated smooth muscle cell differentiation	IGI	J:70266

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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