GO Annotations Graph

• Symbol: Setd7
• Name: SET domain containing (lysine methyltransferase) 7
• ID: MGI:1920501

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0140938	histone H3 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0140945	histone H3K4 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0042054	histone methyltransferase activity	ISO	J:164563
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:194231
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	IDA	J:238299
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	IDA	J:326061
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	IDA	J:194231
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IDA	J:194231
Biological Process	GO:0006974	DNA damage response	ISO	J:194231
Biological Process	GO:0070828	heterochromatin organization	IBA	J:265628
Biological Process	GO:0070828	heterochromatin organization	ISO	J:194231
Biological Process	GO:0070828	heterochromatin organization	IMP	J:194231
Biological Process	GO:0034968	histone lysine methylation	IEA	J:72247
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0051348	negative regulation of transferase activity	IDA	J:194231
Biological Process	GO:0018027	peptidyl-lysine dimethylation	ISO	J:164563
Biological Process	GO:0018022	peptidyl-lysine methylation	IDA	J:326061
Biological Process	GO:0018022	peptidyl-lysine methylation	IDA	J:194231
Biological Process	GO:0018026	peptidyl-lysine monomethylation	ISO	J:164563
Biological Process	GO:0018026	peptidyl-lysine monomethylation	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006479	protein methylation	IDA	J:238299
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247