GO Annotations Graph

• Symbol: Izumo1
• Name: izumo sperm-egg fusion 1
• ID: MGI:1920706

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:240828
Molecular Function	GO:0005515	protein binding	IPI	J:290694
Molecular Function	GO:0005515	protein binding	IPI	J:328498
Molecular Function	GO:0005515	protein binding	IPI	J:160139
Molecular Function	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	IMP	J:235303
Molecular Function	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:155060
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:209568
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0002080	acrosomal membrane	IDA	J:258196
Cellular Component	GO:0002080	acrosomal membrane	IBA	J:265628
Cellular Component	GO:0002080	acrosomal membrane	IDA	J:149637
Cellular Component	GO:0002080	acrosomal membrane	IDA	J:159611
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:290694
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:293874
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:160139
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:328498
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:97563
Cellular Component	GO:0005886	plasma membrane	IMP	J:235303
Cellular Component	GO:0005886	plasma membrane	IDA	J:258196
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098635	protein complex involved in cell-cell adhesion	IDA	J:290694
Biological Process	GO:0007155	cell adhesion	IC	J:97563
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	IMP	J:328498
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	IDA	J:97563
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	IMP	J:209568
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	ISO	J:164563
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	IMP	J:290694
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	IBA	J:265628
Biological Process	GO:0034113	heterotypic cell-cell adhesion	IMP	J:235303
Biological Process	GO:0034113	heterotypic cell-cell adhesion	IBA	J:265628
Biological Process	GO:0007338	single fertilization	IMP	J:209568
Biological Process	GO:0035036	sperm-egg recognition	IMP	J:328498
Biological Process	GO:0035036	sperm-egg recognition	IMP	J:209568
Biological Process	GO:0035036	sperm-egg recognition	IBA	J:265628