GO Annotations Graph

• Symbol: Bloc1s2
• Name: biogenesis of lysosomal organelles complex-1, subunit 2
• ID: MGI:1920939

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	ISO	J:164563
Molecular Function	GO:0043015	gamma-tubulin binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:90887
Molecular Function	GO:0005515	protein binding	IPI	J:90887
Molecular Function	GO:0005515	protein binding	IPI	J:90887
Cellular Component	GO:0031083	BLOC-1 complex	ISO	J:164563
Cellular Component	GO:0031083	BLOC-1 complex	IBA	J:265628
Cellular Component	GO:0031083	BLOC-1 complex	IDA	J:90887
Cellular Component	GO:0099078	BORC complex	ISO	J:164563
Cellular Component	GO:0099078	BORC complex	IBA	J:265628
Cellular Component	GO:0005813	centrosome	ISO	J:155856
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0098574	cytoplasmic side of lysosomal membrane	NAS	J:320078
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:90887
Cellular Component	GO:0000930	gamma-tubulin complex	ISO	J:164563
Cellular Component	GO:0000930	gamma-tubulin complex	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISS	J:201466
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Biological Process	GO:0008089	anterograde axonal transport	IMP	J:187545
Biological Process	GO:0048490	anterograde synaptic vesicle transport	IMP	J:187545
Biological Process	GO:0016197	endosomal transport	IBA	J:265628
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	ISS	J:201466
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	ISO	J:164563
Biological Process	GO:0032418	lysosome localization	NAS	J:320078
Biological Process	GO:0032418	lysosome localization	ISO	J:164563
Biological Process	GO:0032418	lysosome localization	IBA	J:265628
Biological Process	GO:0032438	melanosome organization	NAS	J:90887
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	ISS	J:201466
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	NAS	J:188897
Biological Process	GO:0072384	organelle transport along microtubule	NAS	J:320078
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0051036	regulation of endosome size	NAS	J:319692
Biological Process	GO:0062196	regulation of lysosome size	NAS	J:319692