GO Annotations Graph

• Symbol: Dnm1l
• Name: dynamin 1-like
• ID: MGI:1921256

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051433	BH2 domain binding	ISO	J:155856
Molecular Function	GO:0030276	clathrin binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0030742	GTP-dependent protein binding	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:204661
Molecular Function	GO:0005515	protein binding	IPI	J:277870
Molecular Function	GO:0005515	protein binding	IPI	J:273332
Molecular Function	GO:0005515	protein binding	IPI	J:245375
Molecular Function	GO:0005515	protein binding	IPI	J:286525
Molecular Function	GO:0005515	protein binding	IPI	J:186257
Molecular Function	GO:0005515	protein binding	IPI	J:259757
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:161510
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0120283	protein serine/threonine kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0005905	clathrin-coated pit	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:286525
Cellular Component	GO:0005829	cytosol	IMP	J:200469
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0000139	Golgi membrane	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005874	microtubule	IBA	J:265628
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:230799
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:286525
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:167998
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IMP	J:200469
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IDA	J:208253
Cellular Component	GO:0005739	mitochondrion	ISO	J:73065
Cellular Component	GO:0005739	mitochondrion	ISO	J:73065
Cellular Component	GO:0005739	mitochondrion	IDA	J:259757
Cellular Component	GO:0005739	mitochondrion	IDA	J:224442
Cellular Component	GO:0005739	mitochondrion	IDA	J:307067
Cellular Component	GO:0099073	mitochondrion-derived vesicle	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Cellular Component	GO:0098835	presynaptic endocytic zone membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0099503	secretory vesicle	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IMP	J:259757
Biological Process	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission	ISO	J:164563
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0060047	heart contraction	IMP	J:161510
Biological Process	GO:0048312	intracellular distribution of mitochondria	ISO	J:155856
Biological Process	GO:0048312	intracellular distribution of mitochondria	ISO	J:164563
Biological Process	GO:0051179	localization	ISO	J:164563
Biological Process	GO:0061025	membrane fusion	ISO	J:164563
Biological Process	GO:0000266	mitochondrial fission	IMP	J:200469
Biological Process	GO:0000266	mitochondrial fission	IBA	J:265628
Biological Process	GO:0000266	mitochondrial fission	IMP	J:183839
Biological Process	GO:0000266	mitochondrial fission	ISO	J:73065
Biological Process	GO:0000266	mitochondrial fission	IMP	J:156874
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:155856
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	IBA	J:265628
Biological Process	GO:0090149	mitochondrial membrane fission	ISO	J:164563
Biological Process	GO:0070584	mitochondrion morphogenesis	ISO	J:155856
Biological Process	GO:0070584	mitochondrion morphogenesis	ISO	J:73065
Biological Process	GO:0007005	mitochondrion organization	ISO	J:164563
Biological Process	GO:0007005	mitochondrion organization	IMP	J:259757
Biological Process	GO:0160040	mitocytosis	IMP	J:307067
Biological Process	GO:0070266	necroptotic process	IMP	J:201937
Biological Process	GO:0070266	necroptotic process	ISO	J:164563
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	ISO	J:155856
Biological Process	GO:0016559	peroxisome fission	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:155856
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:164563
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	ISO	J:164563
Biological Process	GO:0050714	positive regulation of protein secretion	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:2000302	positive regulation of synaptic vesicle exocytosis	ISO	J:155856
Biological Process	GO:0012501	programmed cell death	IEA	J:60000
Biological Process	GO:0051259	protein complex oligomerization	ISO	J:164563
Biological Process	GO:0070585	protein localization to mitochondrion	IMP	J:208253
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:1903578	regulation of ATP metabolic process	IMP	J:161510
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IMP	J:259757
Biological Process	GO:0010821	regulation of mitochondrion organization	IMP	J:161510
Biological Process	GO:0010821	regulation of mitochondrion organization	ISO	J:164563
Biological Process	GO:1900063	regulation of peroxisome organization	IMP	J:161510
Biological Process	GO:1900063	regulation of peroxisome organization	ISO	J:164563
Biological Process	GO:1904666	regulation of ubiquitin protein ligase activity	IMP	J:259757
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0048488	synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:0036466	synaptic vesicle recycling via endosome	ISO	J:155856