GO Annotations Graph

• Symbol: Abcb6
• Name: ATP-binding cassette, sub-family B member 6
• ID: MGI:1921354

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015439	ABC-type heme transporter activity	ISO	J:164563
Molecular Function	GO:0015439	ABC-type heme transporter activity	IBA	J:265628
Molecular Function	GO:0140359	ABC-type transporter activity	IMP	J:184574
Molecular Function	GO:0140359	ABC-type transporter activity	IDA	J:241265
Molecular Function	GO:0140359	ABC-type transporter activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:73065
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0020037	heme binding	ISO	J:164563
Molecular Function	GO:0020037	heme binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0046906	tetrapyrrole binding	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0031901	early endosome membrane	ISO	J:155856
Cellular Component	GO:0036020	endolysosome membrane	ISO	J:155856
Cellular Component	GO:0036020	endolysosome membrane	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IDA	J:205748
Cellular Component	GO:0070062	extracellular exosome	IDA	J:305993
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0033162	melanosome membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005740	mitochondrial envelope	ISO	J:73065
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0032585	multivesicular body membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005774	vacuolar membrane	IBA	J:265628
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0098849	cellular detoxification of cadmium ion	ISO	J:164563
Biological Process	GO:0042168	heme metabolic process	ISO	J:164563
Biological Process	GO:0035351	heme transmembrane transport	ISO	J:164563
Biological Process	GO:0015886	heme transport	ISO	J:164563
Biological Process	GO:0015886	heme transport	IBA	J:265628
Biological Process	GO:0006878	intracellular copper ion homeostasis	ISO	J:155856
Biological Process	GO:1903232	melanosome assembly	ISO	J:164563
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	ISO	J:164563
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	IDA	J:241265
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	ISO	J:164563
Biological Process	GO:0043588	skin development	ISO	J:164563
Biological Process	GO:0033013	tetrapyrrole metabolic process	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628
Biological Process	GO:0006810	transport	ISO	J:73065