GO Annotations Graph

• Symbol: Parn
• Name: poly(A)-specific ribonuclease (deadenylation nuclease)
• ID: MGI:1921358

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043169	cation binding	ISO	J:164563
Molecular Function	GO:0004527	exonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	ISO	J:164563
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:134278
Molecular Function	GO:0005515	protein binding	IPI	J:134278
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:72247
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Biological Process	GO:0000495	box H/ACA RNA 3'-end processing	ISO	J:164563
Biological Process	GO:0010587	miRNA catabolic process	ISO	J:164563
Biological Process	GO:0006402	mRNA catabolic process	IEA	J:72247
Biological Process	GO:0110008	ncRNA deadenylation	ISO	J:164563
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA	J:60000
Biological Process	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	IBA	J:265628
Biological Process	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	IDA	J:134278
Biological Process	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing	ISO	J:164563
Biological Process	GO:0051973	positive regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:1904872	regulation of telomerase RNA localization to Cajal body	ISO	J:164563
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	ISO	J:164563
Biological Process	GO:0090669	telomerase RNA stabilization	ISO	J:164563