Actr3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Actr3
ARP3 actin-related protein 3
MGI:1921367

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:67836
Molecular Function	GO:0005515	protein binding	IPI	J:187581
Molecular Function	GO:0005515	protein binding	IPI	J:93351
Molecular Function	GO:0005515	protein binding	IPI	J:93351
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ISO	J:164563
Cellular Component	GO:0005884	actin filament	ISO	J:155856
Cellular Component	GO:0061831	apical ectoplasmic specialization	ISO	J:155856
Cellular Component	GO:0061828	apical tubulobulbar complex	ISO	J:155856
Cellular Component	GO:0005885	Arp2/3 protein complex	ISO	J:164563
Cellular Component	GO:0005885	Arp2/3 protein complex	IBA	J:265628
Cellular Component	GO:0061832	basal ectoplasmic specialization	ISO	J:155856
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0031252	cell leading edge	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0061830	concave side of sperm head	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0000139	Golgi membrane	ISO	J:155856
Cellular Component	GO:0030056	hemidesmosome	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IDA	J:87902
Cellular Component	GO:0061851	leading edge of lamellipodium	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0002102	podosome	ISO	J:155856
Cellular Component	GO:0061825	podosome core	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0001726	ruffle	ISO	J:155856
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	ISO	J:164563
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	IBA	J:265628
Biological Process	GO:0048708	astrocyte differentiation	ISO	J:155856
Biological Process	GO:0008356	asymmetric cell division	IGI	J:172280
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	ISO	J:155856
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:155856
Biological Process	GO:0071346	cellular response to type II interferon	IGI	J:143718
Biological Process	GO:0060271	cilium assembly	ISO	J:164563
Biological Process	GO:0007163	establishment or maintenance of cell polarity	IGI	J:172280
Biological Process	GO:0051321	meiotic cell cycle	IGI	J:172280
Biological Process	GO:0016344	meiotic chromosome movement towards spindle pole	IGI	J:195195
Biological Process	GO:0033206	meiotic cytokinesis	IGI	J:172280
Biological Process	GO:0030517	negative regulation of axon extension	ISO	J:155856
Biological Process	GO:1904171	negative regulation of bleb assembly	ISO	J:155856
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:155856
Biological Process	GO:0030838	positive regulation of actin filament polymerization	ISO	J:155856
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	ISO	J:155856
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:0010763	positive regulation of fibroblast migration	ISO	J:155856
Biological Process	GO:0051491	positive regulation of filopodium assembly	ISO	J:155856
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:155856
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:155856
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:155856
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0099173	postsynapse organization	ISO	J:155856
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0043519	regulation of myosin II filament organization	ISO	J:155856
Biological Process	GO:0051653	spindle localization	IGI	J:172280

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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